This article describes the main directions of socio-economic development of Pavlodar region, provides characteristics and dynamics of the main areas and sectors of the region, including the state of industrial production, agriculture, development of small and medium-sized businesses, the labor market, trade, electricity, heat and water supply, construction. The region is characterized by a progressive and diversified economic structure. In the structure of industry of Pavlodar region the largest share is occupied by the manufacturing industry. The priority direction of development of the regional economy in the context of ensuring its socio-economic development is the development of small and medium-sized businesses