Today, the basis of a successful economy is the full development of all its sectors, the priority of which is the real sector. At the same time, historically, the trends in the development of the real sector of the economy imply the inevitable cyclical nature of the processes taking place in it, affecting, first of all, the activities of its economic entities. Crisis phenomena periodically bring industrial enterprises out of equilibrium. The scale of these phenomena can reach such dimensions that their elimination is not amenable to management decisions, since the effectiveness of the latter can be achieved only at the early stages of crisis phenomena. In modern realities, an effective anti-crisis management system at manufacturing enterprises is an important component of solving strategic problems. Acceleration of the processes of rehabilitation of the post-crisis state of the enterprise requires the development of methods of the most effective levers of anti-crisis management at manufacturing enterprises. In this regard, it is important to determine the key principles and approaches to the formation of anti-crisis management mechanisms. In the scientific environment, when studying anti-crisis management, the institutional component is rarely considered, although recently it has been coming to the fore in terms of the impact on the development of the enterprise. The purpose of the article is to consider the concepts of "institutionalism", "institutional environment" in the framework of crisis management of enterprises, to reveal the organizational and economic mechanism of crisis management of manufacturing enterprises. When writing the article, a systematic approach was used using such general scientific methods as analysis and synthesis, a combination of historical and logical, the method of system analysis The result is the identification of the main problems related to the anti-crisis management of the enterprise, taking into account the institutional component, as well as the offer of tools to prevent crisis situations or reduce the negative consequences of an existing crisis