The nature of a person reflects the history of relationships with the external environment. In the behavior lies the broad meaning of the concept. Accentuation of the nature is a strongly developed feeling in which the priorities and, in particular, the priorities of behavior are manifested. Accentuation is always a certain strengthening of signs, so it is a sign of personality accentuation. Nature formation is a lifelong process. Joint life forms of thoughts, feelings and modes of action. Therefore, along with the formation of a certain life-style image of a person, its " self", a quality that is determined by the appearance.

The article is devoted to the current problem of differential diagnosis of diseases of viral etiology in farm animals. Viral diseases are currently widespread, occupy a leading role in the infectious pathology of farm animals, causing enormous economic damage. Given the magnitude of animal vaccine prophylaxis, in order to increase the effectiveness of antiepizootic measures, the urgent issue i s the development of methods for the rapid and effective detection and differentiation of field and vaccine strains of the infectious rhinotracheitis virus in cattle. The possibility of using a polymerase chain reaction to identify and differentiate a vacc ine strain from epizootic strains and isolators of the cattle infectious rhinotracheitis virus is considered. In the process of research, a PCR-RFLP analysis method was developed to detect the IRT virus in the test material. The PCRRFLP analysis method was used to identify and differentiate the vaccine strain TK-A form epizootic strains and isolators of the cattle IRT virus. The principle of PCR, based on repeated repetition of DNA cycles, annealing and synthesis, which leads to an increase in the number of specific DNA fragments of the pathogen, allows you to take into account the results of PCR in an agarose gel. Analysis time is about 30 hours. The sensitivity of detecting viral DNA is 1-10 picograms (102 TCD). Due to characteristics such as relative simplicity and reaction rate, high sensitivity, specificity and reproducibility, PCR has recently become widespread in basic and applied research in various fields of biological science, including veterinary virology. The results obtained during the studies show that the use of PCR-RFLP allows to differentiate field and vaccine strains and isolates of the IRT virus with a high degree of reliability. The use of PCR -RFLP analysis increases the efficiency and informativeness of studies in the molecular epizootol ogy of cattle RTI, as it allows not only to identify the DNA of different virus strains regardless of their nature, but also to differentiate between them, including differentiating the strain TK-A used for the production of attenuated vaccines against epizootic strains and isolates of the virus.

Main problem: The genus Morbillivirus of the family Paramyxoviridae includes agents of morbilli, plague of cattle, carnivores and small ruminants. Plague agent of carnivores causes a dangerous disease of fur animals and dogs, which in many cases ends in death. The disease is widespread everywhere, including Kazakhstan. In our country, the mixed form of the disease is most common, and the least common is the skin and nervous forms. The chronic course of plague is observed to a greater extent with the nervous form, subacute - with mixed and intestinal, acute - with cutaneous and pulmonary forms of the disease. Goal: Veterinarians have significant difficulties in diagnosing carnivorous plague. Despite the fact that serological methods for diagnosing this infection have been developed and applied for research purposes, the lack of commercial diagnostic preparations on sale significantly restrains their use by practical veterinary workers. Therefore, the diagnosis of plague of carnivores is mainly established on the basis of the symptom complex of the disease and the data of epizootic and pathological anatomical studies, the results of which are largely similar to those in some other diseases of carnivores. Scientific research in the field of means and methods of laboratory diagnostics of carnivore plague, applicable in practical veterinary medicine, is in great demand. Methods: Considering the fact that the carnivores plague and cattle plague are antigenically closely related, studies were carried out to determine the possibility of using means and methods for diagnosing cattle plague for serological diagnosis of carnivores plague. Results and their significance: It has been established that the use of means and methods for diagnosing cattle plague makes it possible to diagnose carnivore plague at all stages of the course of the disease, their use makes it possible to reliably establish a diagnosis of the disease in fur-bearing animals and dogs in a short time after the receipt of samples of material for research, even in cases of mixed viral and bacterial infections; and also to differentiate the plague of carnivores from diseases similar to it - parvovirus enteritis, infectious hepatitis and a number of others.

The data of calculating the actual cost of production are widely used in production management at industrial enterprises, to monitor compliance with the standard cost of production adopted by the enterprise, to identify ways to optimize labor costs and material resources. The level of cost depends on the activity of an industrial enterprise in a market economy: the amount of profitability, the economic efficiency of its activities. The choice of the method of cost accounting and calculating the cost of production depends on the specifics of the technology and organization of production, as well as the requirements of the efficiency of enterprise management. Studying the formation of accounting information when calculating the cost of production by type of product, comparing the level of costs with the revenue received makes it possible to determine the economic efficiency of production. The purpose of this study is to identify the problems of forming accounting information when calculating the cost of production for making decisions to reduce costs. The implementation of the research goal is facilitated by the use of methods of comparative analysis, synthesis, and graphical method for visualizing the results obtained. When considering the cost calculation, attention is paid to the fact that in market conditions there is a need for detailed cost accounting and calculation of the cost of production. If we take into account that in market conditions, prices for products are formed as demand increases, and demand is influenced by external factors, then we can only influence the costs based on the cost calculation. The basis for making effective management decisions will depend on how reliable and to what extent the accounting information is formed. Costs are the main constraint on the profit of industrial enterprises, since the main strategic goal of any enterprise is the mechanism for increasing profits. The ability to achieve this goal is limited by the following internal factors: the complexity of the cost grouping, technological processes, and the impact on product quality. It is necessary to improve the information system, which is based on the data of primary documents, document flow and the order of cost grouping. The proposed measures will contribute to strengthening the control function of the management and, as a result, effective cost management.

Injuries among domestic animals account for 50-70 % of all non-communicable diseases. Fractures of bones, mainly limbs, occur in 44.5 % of cases. The main goal of fracture treatment is to restore normal function and movement of the limb, and the ways in which this is done are varied. Preference is given to methods that do not constrain the movement of the limb, allowing the animal to use it during the treatment period. Purpose: This article discusses the method of bone osteosynthesis, which has proven itself in the treatment of bone fractures, and is relevant today in veterinary medicine. The main study was conducted on the basis of the veterinary clinic "Shans" in Pavlodar. For osteosynthesis, plates for osteosynthesis and screws made of titanium alloy were used. This is due to the fact that when in contact with each other, the metal that fixes bone fragments can oxidize. Animals come to the clinic as a result of injuries that lead to fractures. The most common causes include falls from a height, motor vehicles, careless or rough handling of animals, and contact with other animals. When a fracture is established by obvious signs or if a fracture is suspected, such patients are preliminarily sent for x-rays. Upon receipt of an X-ray image and with the consent of the owner of the animal, osteosynthesis is performed. When accessing bone fragments, the incision was made along the muscle fibers. Osteosynthesis was performed according to the method described by V.M. Shapovalov (2009). The general condition of the animals after osteosynthesis was restored after 3-5 days. All animals, after bone osteosynthesis, completely relied on the limb. Contractures of adjacent joints and muscle atrophy were not determined. Plain osteosynthesis of the femur, in the presence of the necessary instrument and consumables, is not very difficult to perform. Performing bone osteosynthesis in the early stages makes it possible to include the limb in the locomotory act, as a result of which the animal actively uses the limb during the rehabilitation period.

The concept of resilience, the ability to withstand crises and adversities and recover from them, has valuable potential for research, intervention and preventive approaches aimed at strengthening the family. There are many paths to relationship resilience, varying depending on different forms of family, psychosocial problems, resources and constraints. Shared beliefs that promote alignment and cooperation are vital to overcoming adversity. Measures to increase the resilience of families are of timely importance to overcome the rapid social changes and uncertainties that families face today. According to research by sociologists and family consultants, each family goes through several stages of development, and the transition from one to another is usually accompanied by a crisis. It is generally believed that domestic difficulties lead to complications in family life, first of all. The purpose is to identify the types of problems and causes leading to crisis situations in marriage. In this regard, the methods such as analysis of literary sources on this topic, generalization, synthesis, psychological experiment, diagnosis of the psychology of family crisis by H.I. Olioirovia, T.A. Zinkevii-Kuzemkin, T.F. Velenta were used. The authors of the article come to the conclusion that stress is a part of life, and the slings and arrows of misfortune hit all families throughout their lives. The concept of family resilience confirms the reparative potential of all families and offers a valuable basis for research and clinical practice. Just as families face a variety of challenges, there are many ways to increase family resilience. By understanding key processes, clinicians can mobilize untapped resources, allowing families in distress to cope with difficulties more effectively and recover through their mutual support and cooperation. Therefore, it is necessary to understand the patterns of crisis situations and the socio-psychological causes of their occurrence.

In the dairy market of Kazakhstan, the demand for mass-produced dairy products is decreasing and expanding to innovative fermented milk products for functional nutrition. The main feature of the new technology is multicomponent formulations, which include the main raw materials and biocorrectors, ensuring their high biological and nutritional value. New dessert products are prepared on a dairy or protein basis using vegetable ingredients, fermented with strains of dry starter cultures of direct application or immobilized starter culture Bifimm probio. The purpose is to apply immobilized living cells of pure cultures of lacto- and bifidobacteria as a biocatalyst for the fermentation of dairy-vegetable media. During the study, the method of immobilization of microbial cells in biopolymer gels was used. The most effective method is the inclusion of cells in an aqueous solution of biopolymers with a concentration of 25 %. For immobilization, pure cultures of lactic acid and bifidobacteria were selected in the gel as part of the concentrates "BK-Altai-LS Bifi", "Poleznaya Partiya", "Genesis", "Narine", "Bio-yogurt Vivo", and the main prescription ingredients were selected: milk with a mass fraction of fat of 1 %, 2.5 %, 3.2 %, natural grain additives, jams, juices, nuts. Formulations, technological schemes and production methods, prototypes were developed, quality and safety indicators were determined. Studies have shown the effectiveness of immobilized starter cultures in the formation of fermented dessert products. Out of 20 prototypes with the best indicators, 5 samples were selected, in which the optimal ratio of milk, probio Bifimm starter cultures and biocorrectors averaged 70:20:10. The quality and safety analysis showed that new fermented milk products using immobilized starter cultures have a positive effect of more than -70 % compared to direct-use starter cultures, have functional properties and can be used for healthy nutrition in Kazakhstan.