The digital transformation of the education system is accompanied by the active introduction of artificial intelligence technologies into the educational environment. Intelligent digital systems are used to analyze educational data, personalize learning, and optimize the educational process. At the same time, their application requires consideration of the psychological characteristics of learners and the pedagogical conditions of the functioning of the digital educational environment. In this regard, the study of psychological and pedagogical factors ensuring the effective use of artificial intelligence technologies in educational practice becomes particularly relevant. The purpose of the study is to identify and substantiate the psychological and pedagogical conditions for the effective use of artificial intelligence technologies in the digital educational environment. Materials and methods. The study employed methods of analysis of scientific literature, generalization of domestic and international experience in the implementation of intelligent educational systems, as well as analysis of practices of using digital platforms and elements of artificial intelligence in the university’s digital educational environment. Results. The study identified psychological and pedagogical conditions that ensure the effective application of artificial intelligence technologies in the educational process. These include the digital competence of teachers and students, pedagogical integration of intelligent systems into the structure of learning activities, adaptation of educational content, and the formation of a psychologically supportive digital educational environment. The role of intelligent systems in increasing students’ cognitive activity, developing their independence, and optimizing educational interaction in the digital environment has been substantiated. Conclusion. The obtained results clarify scientific ideas about the possibilities of using artificial intelligence technologies in education and can be used in the development of models of the digital educational environment, as well as in the organization of psychological and pedagogical support for students in the context of the digitalization of education.