In this article it is considered a compliance assessment of developing industrial sectors of the country to the principles of «green» economy based on the example of the petrochemical complex of the Republic of Kazakhstan. Relevance of the research is caused by the need to build «green» low-carbon economy. The implementation of «green» economy concept will be a strong incentive for technological renovation for the numbers of industries. The directions of the «green» economy in the petrochemical industry of the Republic of Kazakhstan have been determined, as well as an analysis of international experience to implement the principles of «green» economy in the petrochemical industry has been carried out.

This paper evaluated the governance of the social sphere of the Pavlodar region. Based on the analysis of the main social indicators, identified the strengths and weaknesses of the region in this area, as well as identify opportunities and threats that affect the development of the region as a whole. In a changing social and economic relations, the issues related management and development of a regional social complex. Their decision depends not only on the success of social reform, but also the normalization of the socio-political situation in Kazakhstan.

The article presents the results of studies conducted at the veterinary clinic «Jean» in the city of Pavlodar. It is noted, that for the period 2013-2017. 348 cases of disease in dogs were registered by pyroplasmosis – a protozoal disease caused by parasitic organs of the genus Piroplasma. The authors described the clinical symptoms of disease in animals, as well as the nature of the flow of infectious diseases.

Currently, the system of secondary education is moving to the updated content of education, accompanied by a change of the state educational standards, standard curricula, educational and methodical complex. The article notes the special importance of the course of Informatics in the system of secondary education in modern conditions, an attempt is made to analyze the developed electronic applications in Informatics for students of 3, 6, 8 classes

Main problem: The genus Morbillivirus of the family Paramyxoviridae includes agents of morbilli, plague of cattle, carnivores and small ruminants. Plague agent of carnivores causes a dangerous disease of fur animals and dogs, which in many cases ends in death. The disease is widespread everywhere, including Kazakhstan. In our country, the mixed form of the disease is most common, and the least common is the skin and nervous forms. The chronic course of plague is observed to a greater extent with the nervous form, subacute - with mixed and intestinal, acute - with cutaneous and pulmonary forms of the disease. Goal: Veterinarians have significant difficulties in diagnosing carnivorous plague. Despite the fact that serological methods for diagnosing this infection have been developed and applied for research purposes, the lack of commercial diagnostic preparations on sale significantly restrains their use by practical veterinary workers. Therefore, the diagnosis of plague of carnivores is mainly established on the basis of the symptom complex of the disease and the data of epizootic and pathological anatomical studies, the results of which are largely similar to those in some other diseases of carnivores. Scientific research in the field of means and methods of laboratory diagnostics of carnivore plague, applicable in practical veterinary medicine, is in great demand. Methods: Considering the fact that the carnivores plague and cattle plague are antigenically closely related, studies were carried out to determine the possibility of using means and methods for diagnosing cattle plague for serological diagnosis of carnivores plague. Results and their significance: It has been established that the use of means and methods for diagnosing cattle plague makes it possible to diagnose carnivore plague at all stages of the course of the disease, their use makes it possible to reliably establish a diagnosis of the disease in fur-bearing animals and dogs in a short time after the receipt of samples of material for research, even in cases of mixed viral and bacterial infections; and also to differentiate the plague of carnivores from diseases similar to it - parvovirus enteritis, infectious hepatitis and a number of others.

The main problem: This article is devoted to the key problems of the fuel and energy complex of the Republic of Kazakhstan: 1) lack of production capacity to meet the growing demand for energy and fuel from the economy and the population. Increased demand for electricity and heat, which will require the commissioning of new generating capacities.There is already a shortage in the fuel markets. Modernization and bringing the existing oil refineries (hereinafter referred to as refineries) to full capacity will not allow providing the domestic market until 2030; 2) the export orientation of raw materials, the dependence of the economy on the export of energy resources. In order to attract technology and investment in the oil and gas and nuclear industries, agreements on the extraction of energy resources were concluded with international export companies. In the medium term, Kazakhstan may face a shortage of oil for domestic refineries, if measures are not taken to stimulate its refining within the country. The uranium mined is fully exported; 3) high energy intensity of the economy, low level of energy efficiency. There is a high potential for increasing the efficiency of energy use both in the electric power industry and fuel production, and at the level of final consumption – in industry and housing and communal services; 4) decrease in the replenishment and quality of the resource base in the oil and gas, coal and nuclear industries; 5) low environmental friendliness of technologies used in the fuel and energy complex. Purpose: The purpose of the article is to reveal the problem in the field of ensuring the fulfillment of international obligations between different countries and their own energy sufficiency by gradually changing the structure of energy production. Methods: Studying the experience of increasing the efficiency of the use of energy resources and energy saving as a priority of the state policy of the country. Analysis of production capacity with a constantly forecasted shortage of primary energy resources and insufficient growth of capacity for the production of electricity and heat. Consideration of the possibility of compensating for the shortage by saving energy resources, increasing tariffs for energy carriers, as a stimulating factor for their effective use. Results and their significance: The results of this article will reflect the problems of energy, as the most important driving force of global economic progress. The well-being of the people depends on the state of the country's energy sector, therefore there is an urgent need to solve the emerging problems. The global energy problem is, first of all, the issue of stable and efficient supply of fuel and energy to mankind. Today, the energy sector of Kazakhstan is focused on fuel resources, since the country is provided with hydrocarbons and other energy resources. About 72 % of electricity in Kazakhstan is generated from coal, 12,3 % from hydro resources, 10,6 % from gas and 4,9 % from oil. Thus, the four main types of power plants generate 99,8 % of electricity, while alternative sources account for less than 0,2 %.

Main problem: At present, service, decorative and hunting dog breeding is intensively developing in Russia and in the Tula region. So, in 2020, 119 high-breed puppies were registered in the Book of Pedigree Breeding, and in 2021 already 164 puppies, mostly decorative and service breeds. Thus, the number of pedigreed dogs susceptible to various infectious diseases is increasing annually. Canine distemper is one of the most widespread viral diseases of dogs all over the world, including in Russia. Analyzing the "Patient Admission Logs" of veterinary clinics in the city of Tula, it was found that 44 % of dogs that fell ill with diseases of infectious etiology were diagnosed with canine distemper. Purpose: The aim of our research was to study the epizootological features of the course of canine distemper among dogs in the Tula region of Russia. To achieve the intended goal, it was necessary to solve the following problem: to analyze the breed and age factors for the incidence of canine distemper. Methods: Analysis of data from private veterinary clinics reporting on the incidence of small domestic animals was used. Results and their significance: As a result of studying the epizootic situation of canine distemper among dogs, the following data were obtained: The disease is observed throughout the year and has the character of undamped fluctuations subject to sharp seasonal changes. The maximum number of diseased dogs in all years of observation is recorded in March - 6.2 cases per 1000 individuals. It has been established that among the infectious diseases of dogs, distemper occupies the first place, and there is an annual increase in the number of dogs with distemper.

The production of vaccine preparations before release requires standardization of their immunobiological parameters, especially safety and immunogenic efficacy. An indicator of the immunogenic effectiveness of the lumpy skin disease vaccine is the resistance of vaccinated cattle against the virulent virus. However, according to preliminary studies, the virulent control virus did not always cause clinical disease with characteristic symptoms when infected subcutaneously. The purpose is to develop a biological model in the form of a complex consisting of a pathogenic virus, a method of infection and a susceptible animal to assess the immunogenicity of a lumpy skin disease vaccine. Local cattle, intact from lumpy dermatitis, were used to reproduce lumpy dermatitis and develop the causative agent of the disease. As the initial infectious virus, we used a 20 % tissue suspension of nodules (skin nodules) obtained from cattle that fell ill with lumpy dermatitis in the field in the Atyrau region in 2016. As a viral mass to control immunogenicity, a 20 % suspension of skin nodules and edematous skin tissue at the site of the pathogen injection, obtained after the “refreshment” of the virus in animals, were used. The disease was reproduced by infection with the test suspension of the virus intradermally, subcutaneously, intravenously at a dose of 0.5 cm3 and titration on the skin of the animal. The effectiveness of the biological model was assessed by morbidity, severity of the course and severity of the manifestation of the disease. During primary intradermal infection with a field isolate of the virus, the disease manifested itself in one of three animals in the form of hyperthermia, depression, lacrimation, and the appearance of several nodular nodules in the skin of animals. The refreshed tissue virus caused clinical disease both in subcutaneous, intradermal and intravenous infection. But the clinical signs of the disease were more pronounced with intradermal inoculation of the virus, and with intravenous inoculation, it manifested itself in a more severe form with a fatal outcome. Inoculation of the virus intradermally into different areas of the skin led to the development of an independent skin lesion in each infected point in the form of painful edema, followed by necrosis, the size and intensity of which depended on the dose of the injected virus. This development of skin pathology made it possible to work out a method for determining the virus titer in vivo. The tissue virus obtained from the edematous tissue at the site of the pathogen injection was guaranteed to cause clinical disease in cattle during intradermal inoculation and made it possible to evaluate the immunogenic efficacy of the produced batches of vaccine against lumpy dermatitis.